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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0af020affbb6dcd7d529834f8b36ce5e7be0fb420acfa371e9a4b813d10fda89' 
  AND token = 'UO/aKhuu5W5LzwfICY7Hy1iE7ZHdvzm6KmMcxnaN+pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}