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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd545e671f19197e4d47db8399e7888db359eeb91988ad8ecbd809383e4825e48' 
  AND token = 'ldhRaUgDCTfLnWhXxiL4+Aiufmzj79SYXjAlGnAcD1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}