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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af139ca15f42f3c22819aa02bb76700137c0a82f959ffdfa2be410f0d719175d' 
  AND token = '+EunL6duGXWHpyhXEi4c2CwyhQtWacdt86CfO31lVIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}