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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e50710df339070660476f4400ca5b025f716580b3c2ace174a622a549d8c1d' 
  AND token = 'QLX8R35vP7U3lHq1As7IR8/Rd/3pamIqMSUOvOY95y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}