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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d46c67b2d0e2ba8135a5cb47f4692a8679829df6f3d4d47a55517857ed6c697' 
  AND token = 'vpYFt1Ma/ommnu3owtizlwHQN9r4aApRevoHVs06eiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}