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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba390b7438991434384020758cf09aedf67e0086ae31606d83cb5e772da430d6' 
  AND token = 'O8GHcpoTTxHgN+mAtrigFTl21OPtATVjGEeZmQ4Ejnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}