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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3be5a8815ee0002d21ff3c250a799bb00de503f0d040b1a8d217e4d8aa09a8' 
  AND token = 'xYY0mi7dgyBHDs7GxoTOfZuAX3AK0Luus4H//nZwvcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}