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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c01f9e1e3aeb6947ec434a908b692a5e308f31c2a08c9eb6a3e31c4c6e837a' 
  AND token = 'sLbpXtYG6efF6Wicu+Q8umdz15ySQRDTK0iqeSQUxc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}