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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '761266473e23f69269f1f34ccbda9a4c0290a8dfb3e736a3310cafa377447910' 
  AND token = 'SYR0OvEfUBx4sk/yPtliGrZ3Vrctzej7jmR+IXrR/iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}