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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0260c9aded37c88a3a9c4724e27a094dc28faad7307817e50fc11173be12fcf7' 
  AND token = '+Cw4FmM6LgWANk2WKI0D5Of9z9Kw3xVmB3r+x58FfOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}