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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb750ecd8a69fceb3834026a03ea1feed8d6cc7d0c3f40ae529a9ece1a4f839' 
  AND token = '75L7mnmRo7HAoyOnm0UqfWGnlJOqdTeAMe5uOaFT+bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}