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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e0db1d5e7406a85a650dc110479c6017526c75d8902e09be6f64f18075b7d4' 
  AND token = 'bCaKm+qYKKLc1W3FucNgTcZaj6WSNY0m1oV4TvYZiCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}