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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7421af0604af4fd92f993a75124327f02e1efa68d35058127989061fd3f4c67' 
  AND token = '2gLV1a627ggh5D2Q+FAdIryTUxiLIetn5jTbiAGDZcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}