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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '297437e7c123a5e21142cf532d71ff96b992a678a03fdea4702ba99833d00146' 
  AND token = '9PtkMkEV/qjaLeB3L+IQ5PbN/inUJy6lV/2HfJj6zvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}