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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33212043864ccd78c21fdde4b93cf66e1f39a1f9e1fdf1e69eb446eff6b5a9f4' 
  AND token = 'P6AE+odKWr4TZ6KY09UW0Gs7sUKFUB4QgD6Din4aNEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}