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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddf44630f72aa3c79f299eee96c0559f6b12c225c1a1fd2c88fd1dd56f1c426b' 
  AND token = 'wWYuoUdzzUIWvNtrJIf74AnWjH/t1aL+D/RqyFA4/EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}