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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74cdaefb13b3b202099b69c1a3f09f7311d258a1c1379facadfaec4548549f58' 
  AND token = 'FajSJ/AB7HY3pkSC+ZcC/hR6eimC9ucYE/g19DlncZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}