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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246ab16450646735c02a5979fa0ed3fb8d78e8e63f3b28549d2c0f39d90fa385' 
  AND token = 'cAT81okt41sMQQVJWExWXh8ndk5u30j/0f+W06KnDJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}