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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '562b7480e71f7a438faee798d5609fe06f3aea609b7e3078f7a9e0c38feabd4b' 
  AND token = 'HOFVvfFzTsEDtngvsYw+IFHEGc8MeBCCiOGGipJBPu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}