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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5901f933507e007f3aa664780299b4c5a5eb2b6fe94738a131a9660f3387f837' 
  AND token = 'FWOcPK7Oyk9wIQHY4bGRCwE13exMuard1TFPWYWZi7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}