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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f0301d0a291ba9c36bad031bd4b4eadec446b0d6e252d557e437d1ba6dc581' 
  AND token = 'h0isZ/z0I3OEP1jlMvpWcOvH7UrDHyYfpx3Vj5SOoKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}