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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc6cbe5ad8300f123424b5bcf3393033f0fd81801f95e9247dcd0b73c557bcd' 
  AND token = 'RUe9FGyutKJA0mZDUIC/lK2lyXJkLdZzEuCR1/4hQ9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}