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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38aa74bd1cb405da74420c43022c25fff9d3ed30d5cb1ead578660385a2f3559' 
  AND token = 'Dn01p5L785b3kcUItzsRxh6igGVW3sCfF8a5F47MpZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}