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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd52e6688920c1afc052e672f3eb13508cf7882345b8784cdb454ea8969dd61' 
  AND token = '6Vuzj2/eA2xenoSR+8FGuE7Um0+Fex+zRxFuA6OZJb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}