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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c4da14ca2d51a6656a0297d8b57279949315ec6e6bd1e057a67c48bd631969a' 
  AND token = 'Nnr2UJ1eGrg016Z3mGV4FqCMY9JuL5Ae3Rvf+47qgx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}