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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8166c1f434f4a5570a11426472f48f361ed907aca03e7504b6b10c4ce6c60aaf' 
  AND token = 'w2q9Ur4H8VqZdOJiVP+6XUQeLtMBIsiRknA7tcHoH1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}