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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d4f785d6b08691f2b77304ae960890704372c393816fc208adeff6f0f4e69e' 
  AND token = '9+fQdEhUyi9EGo2hPBIKxE3TKIJzkOhaI1H+A0H7MIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}