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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01d20e88561dbed068aa64d97a499438ba274125abc5b211e2822fc17599b7e' 
  AND token = '39B0ReJmkIiKE6qu3bjotF25kVyzeHJi+EN/9c4HzCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}