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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1894279530dfe95c26192cf98dfb788cd2a2e921cb172427b39f14196d48fb2f' 
  AND token = 'O7i9x8sMiWo733T0B1IF0i33tXUFAfOIAWz6viUBHZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}