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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd49d8c3a64cb5ffd2d6d65233400a09976a89104bc156f1e28462cca502b6cc' 
  AND token = 'oyNIseeMBy9RFdVqi2dWWPOxDdawT0wN1peI/0qsRUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}