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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61b0ec794fbe763264e5afec90f943e5ccc6cb280bd2d044c89ee50bdb3e7192' 
  AND token = 'ihFQEWQ67M4r3X8PzlB1g7lQLeMC1eJ+c9hbQH9x/j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}