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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a648c9cc0df9dd1d849d444eb197bf2825df689b6bca63fa84276cf7fb8527ee' 
  AND token = 'P4mqnQOhgbfYs+Bz42vF151Zos87TGaXqbYqt7iDDn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}