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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a523512a59dc9441bd6ef3873a931b77aa9f705bccd326506b7bf6913e9918e' 
  AND token = 'vOEEp+XVXVQiEgTODl8cG0/tb0suHuGekYAmffWo0jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}