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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250750d868a7172af9f01e72bd1456d000a38ba4721f075414e5b319f54f69dd' 
  AND token = 'whig/WGIOR495Zvz9FHyCJgclnMSR8d7xHhsf5lCEm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}