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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a18c3b7dccf2a100ea679cc07965131ef6f662203e88d48c668b3313f66e652' 
  AND token = '0Y4I4FM+VXW5EKmGsdmU+nLzd3CNHe14bzwXhKj0CNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}