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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4151df9e3015aba0556e02076e3a519414b38b994b72afd281dc66a27d9baf46' 
  AND token = '2O//kev4iNDIawYAtyykRpLm3NydewxPh0fyxq4bKpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}