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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55998c0c440a98465f48048a9cb88a2ea8d8bb020b89c68e1d0a0d31168fd916' 
  AND token = 'MC7KYC2tl0rl5x79jZfKcpzwO+GxlNoShya525cuzpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}