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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '663b0d10176f7509e45c4c397c712921bdec901a4134e9fb66fb824ba72c09d2' 
  AND token = 'zU7qMAr1L/dbyD9aMgAbjD/57ihUpM15FChOQ/hSQkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}