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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ee6f27766d8e866d571d01c0bc448c538d9c0af580071d44d4251c01902704f' 
  AND token = 'pF4x/ntzvYMQ1iY9Wb35bDku5FznVZse1CBxgG4jQYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}