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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224649c8492531f9eac39dd8629e609bc8e24730b91e62a10b58a432e566a5f9' 
  AND token = 'Z1O12VtHfXX7X8Buh+xe4/ibReZbo9j9eFYRsY/JR2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}