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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4201af75e5ed7140491a4cc3d13b77a7d879ebdd52b2bb8b99eab079cca28210' 
  AND token = '04v43gc8bhqaBekoMPK2fCOYghwcvsqsA7nqLh6a478=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}