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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e548208186a4f8d5dfcc71fc102cf02f7653fedf6a27ed510034e593c7567d63' 
  AND token = 't0JAmn8aEB6ggWQIlWfkjG5ggezt+wyMd+RlzU3dWOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}