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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e417a0a17955b103d55ff6a8d2e6dc0349c6467c83ed78a9a0ca845f8b4aebc4' 
  AND token = '1/RJf/LUQKdwZG3YeT2xIv0TiJ6cqfcTXbXE/RZE5GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}