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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c81c0c1cc9e6bdcda149ec64f9032e2354bbc4a20d65914bdbc517d1ed7f0e' 
  AND token = 'rMXHwUksAesLVJ65VPyWrW4LedIKKCFVXy6jv9vNT2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}