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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287868bca432a7fafeb08b81f4aedabfb67d53a31ecc7b09a4f50e1c75183bfc' 
  AND token = '6MBOByigmc3GTA1vV0IBAr2RcGGPRpAz7e1XXvGLB0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}