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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b0452d07a5eaf5cdbf3552adf11352c8852ec49720de862e484c0ed76cd48a1' 
  AND token = 'xF1DR7+sGawdLEqpCJ0O3o/ZGtPVksOOn9ZGR6y0N3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}