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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32191608b4268f65f3ad04437e6b2fe831db684531f741e84ca54c92a7675c00' 
  AND token = 'OpDoo+lnFil5xlCS/JIOeyRdSRPF78leLGzVP0V8TFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}