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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3b55139901dc003c50bcc99f7bc9c0dbe6d9087a0568b6060c81e70d0266be' 
  AND token = 'aMOzR6gmPESKhADk4AlWzRHf+dd2qIdYCLNRlgyIg/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}