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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3baa5f8f6540dad0c6f72959291620a0fa2da60e735b1b2aab887a1877d86a' 
  AND token = 'v+4fSKDR9YpGeoFJ6TkAm0dDdk6W3WcZzWbFaWhTbvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}