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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294e9ad0a15542067e80585670b75db3e891029a2e7d9510fa75e4b1f58186e7' 
  AND token = 'tP/YaI6T4366/GHeqZVENSmv9G4jaWzqFEqc/q3RJHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}